Search results for "Selection criterion"

showing 7 items of 7 documents

Educomunicación y noticias científicas en los libros de Ciencias para el Mundo Contemporáneo.

2017

La asignatura Ciencias para el Mundo Contemporáneo contiene finalidades y objetivos ligados al desarrollo de las alfabetizaciones científica y mediática de todos los estudiantes de Bachillerato. En esta materia obligatoria el desarrollo de la competencia científica se plantea desde los conocimientos y habilidades científicos necesarios para comprender, participar y tomar decisiones sobre las controversias sociocientíficas en los medios de comunicación (Educomunicación). En este artículo mostramos un análisis de la presencia, del contenido y del tratamiento de las noticias científicas incluidas en los libros de texto de esta asignatura. Los resultados ponen de manifiesto que sólo cinco edito…

Sociology of scientific knowledgeDidácticas aplicadasMedia studiesNewspaperPoliticsGeographyContent analysisComputingMilieux_COMPUTERSANDEDUCATIONPsicología y educación:PEDAGOGÍA [UNESCO]Selection criterionMissed opportunityUNESCO::PEDAGOGÍACompetence (human resources)Humanities
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Molecular Classification of 5-Amino-2-Aroylquinolines and 4-Aroyl-6,7,8-Trimethoxyquinolines as Highly Potent Tubulin Polymerization Inhibitors

2013

Algorithms for classification and taxonomy are proposed based on criteria as information entropy and its production. It is classified a series of 5-amino-2-aroylquinolines (AAQs) and 4-aroyl-6,7,8-trimethoxyquinolines (TMQs) combretastatin analogues for anti-cancer activity. 5-Amino-6-methoxy-2-aroylquinoline AAQ showed anti-proliferative activity more potent as compared to combretastatin A-4 (CA4), against various human cancer cell lines and a multidrug resistance (MDR) cancer cell line. On the basis of AAQ/TMQ structure–activity relationship new derivatives are designed. The AAQs/TMQs are classified using nine characteristic chemical properties in molecules. Many classification algorithms…

Combretastatinchemistry.chemical_compoundStatistical classificationMolecular classificationchemistryStereochemistryQuinolineBiologySelection criterionCombinatorial explosionHuman cancerTubulin Polymerization InhibitorsInternational Journal of Chemoinformatics and Chemical Engineering
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Molecular Classification of N-Aryloxazolidinone-5-carboxamides as Human Immunodeficiency Virus Protease Inhibitors

2015

Algorithms for classification and taxonomy are proposed in this chapter based information entropy (IE) and its production. The 38  N- aryloxazolidinone-5-carboxamides (NCAs), for human immunodeficiency virus (HIV) protease (PR) inhibition, are classified using seven characteristic chemical properties of different moieties: R 1/2 , R 3–6 on different phenyls and R 7 . Many classification algorithms are based on IE. When applying some procedures to moderate-sized sets, excessive number of results appear compatible with the data and suffer combinatorial explosion. However, after the equipartition conjecture (EC), one has a selection criterion among different variants that results from classifi…

CombinatoricsCrystallographyStatistical classificationProteaseMolecular classificationmedicine.medical_treatmentmedicineHuman immunodeficiency virus (HIV)Human Immunodeficiency Virus Protease InhibitorsBiologySelection criterionmedicine.disease_cause
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Planning Rehabilitation Actions on Water Distribution Networks in Condition of Data Scarcity

2011

The paper shows a viable approach to the selection of water networks rehabilitation actions, in condition of data scarcity and uncertainty, based on the use of four concise performance literature indices, allowing the analysis and identification of efficient, reliable and robust rehabilitation alternatives, even if assessed on the basis of a relatively small amount of data. A promising statistical sampling method of water consumptions is also described, that may be fruitfully employed within the proposed approach for drafting water balances at network district scale in order to quantify the extent of leakages. The illustrated case study shows that the selected indices are capable to describ…

EngineeringMains electricityRehabilitationDistribution networksOperations researchbusiness.industrymedicine.medical_treatmentmedia_common.quotation_subjectEnvironmental resource managementWater demandScarcityRobustness (computer science)medicineWater distribution networks rehabilitation actions data scarcity performance indices resiliency water balances network samplingService efficiencySelection criterionbusinessmedia_commonWater Distribution Systems Analysis 2010
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Comparison of selection criteria for milk yield traits of Valle del Belice dairy sheep.

2006

Abstract The objectives of this work were to investigate alternative selection criteria for milk yield traits in the Valle del Belice sheep breed, which are either corrected for lactation length or not affected by lactation length, to estimate genetic parameters for these alternative selection criteria and to compare the estimated breeding values. The genetic correlations show that corrected milk yield (CMY), maximum test-day yield (MTY) and milk yield at hundred days (MYH), are moderately or weakly correlated with lactation length (LL) ( r g  = 0.58, 0.16 and 0.39, respectively). Higher genetic correlation was found between total milk yield (TMY) and LL ( r g  = 0.73). Rank correlations be…

Animal scienceMilk yieldmedicine.anatomical_structureGeneral VeterinaryLactationmedicineAnimal Science and ZoologyBiologySelection criterionSheep breedGenetic correlationSelection (genetic algorithm)
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Toxicity as prime selection criterion among SARS-active herbal medications

2021

We present here a new selection criterion for prioritizing research on efficacious drugs for the fight against COVID-19: the relative toxicity versus safety of herbal medications, which were effective against SARS in the 2002/2003 epidemic. We rank these medicines according to their toxicity versus safety as basis for preferential rapid research on their potential in the treatment of COVID-19. The data demonstrate that from toxicological information nothing speaks against immediate investigation on, followed by rapid implementation of Lonicera japonica, Morus alba, Forsythia suspensa, and Codonopsis spec. for treatment of COVID-19 patients. Glycyrrhiza spec. and Panax ginseng are ranked in …

2019-20 coronavirus outbreakmedicine.medical_specialtyRelative toxicityCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pharmaceutical ScienceReviewSARS-CoV-2 severe acute respiratory syndrome coronavirus 203 medical and health sciencesCytochrome P450 Phytochemicals0302 clinical medicineSOD superoxide dismutaseDrug DiscoveryMedicineAnimalsHumansOral applicationIKK inhibitor of κB kinase030304 developmental biologyPharmacologyRational phytotherapy0303 health sciencesPublic healthCOVID-19 Coronavirus disease 2019JNK c-Jun N-terminale kinaseNO nitric oxidePlants MedicinalTraditional medicineToxicityACE2 angiotensin converting enzyme 2business.industrySARS-CoV-2Public healthCOVID-19Th2 T helper cells type 2NF-κB nuclear factor- κ B cellsComplementary and alternative medicine030220 oncology & carcinogenesisToxicityMolecular MedicineCYP cytochrome P450 monooxygenaseHIV-1 human immunodeficiency virus 1businessSelection criterionMAPK mitogen-activated protein kinaseDrugs Chinese HerbalPhytomedicine
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Molecular Clustering of Phenylurea Herbicides: Comparison with Sulphonylureas, Pesticides and Persistent Organic Pollutants

2014

Chromatographic retention times of phenylurea herbicides are modelled by structure–property relationships. Properties are hydration free energy and dipole. Bioplastic evolution is an evolutionary perspective conjugating the effect of acquired characters and relations that emerge among evolutionary indeterminacy, morphological determination and natural selection principles. Classification algorithms are proposed based on information entropy and production. Phenylureas are classified by Cl2, O2 and N2 presence; their different behaviour depends on the number of Cl atoms. When applying procedures to moderate-sized sets, excessive results appear compatible with data and suffer a combinatorial e…

PollutantStatistical classificationMolecular classificationChemistryEnvironmental chemistryPrincipal component analysisGeneral MedicinePesticideSelection criterionBiological systemCluster analysisCombinatorial explosionEvolving Trends in Engineering and Technology
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